Intracorneal inlay to correct presbyopia: Long-term results

• Published in: Journal of cataract and refractive surgery Vol. 37; no. 7; pp. 1275 - 1281
• Main Authors: Ylmaz, Ömer F., MD, Alagöz, Neşe, MD, Pekel, Gökhan, MD, Azman, Engin, MD, Aksoy, Ebru F., MD, Çakr, Hanefi, MD, Bozkurt, Ercüment, MD, Demirok, Ahmet, MD
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.07.2011; Elsevier
• Subjects: Biological and medical sciences; Contact Lenses; Cornea - surgery; Emmetropia; Female; Follow-Up Studies; Humans; Male; Medical sciences; Middle Aged; Ophthalmology; Presbyopia - surgery; Prospective Studies; Prostheses and Implants; Prosthesis Implantation; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Surgery of the eye and orbit; Treatment Outcome; Vision disorders; Visual Acuity - physiology; Eye disease; Cornea; Treatment; Vision disorder; Surgery; Refractive error; Presbyopia; Ophthalmology; Long term
• ISSN: 0886-3350; 1873-4502
• DOI: 10.1016/j.jcrs.2011.01.027

Purpose To evaluate the long-term visual results of Acufocus ACI-7000 (now Kamra) intracorneal inlay implantation in presbyopic phakic patients. Setting Beyoğlu Eye Training and Research Hospital, Istanbul, Turkey. Design Clinical trial. Methods This study comprised patients with emmetropic or post-laser in situ keratomileusis (LASIK) presbyopia. Patients had an uncorrected near visual acuity (UNVA) of 20/40 or worse, correctable to 20/25 or better at distance. The inlay was implanted on the stromal bed after the LASIK flap was relifted or a flap created. The inlay was centered on the presurgical position of the first Purkinje reflex. The main outcome measures were distance and near vision and the complication rate. Results The study enrolled 39 patients aged 45 to 60 years. At the 4-year follow-up, all patients (N = 22) had 2 or more lines of improvement in UNVA with no significant loss in distance vision. The mean final UNVA was 20/20 (Jaeger [J1]); 96% of patients could read J3 or better. The uncorrected distance acuity was 20/40 or better in all eyes. Five patients had cataract progression, and 2 had a change in refractive status. No eye with an intracorneal inlay had intraoperative complications during cataract extraction. Four inlays were explanted during the study. There were no severe corneal complications that affected final vision. Conclusion Intracorneal inlay implantation was an effective, safe, and reversible procedure for the long-term surgical treatment of presbyopia. Financial Disclosure No author has a financial or proprietary interest in any material or method mentioned. Additional disclosure is found in the footnotes.