Ischemic preconditioning of the lower extremity attenuates the normal hypoxic increase in pulmonary artery systolic pressure

Highlights ► Hypoxic increases in pulmonary pressures are attributed to local vasoconstriction. ► Ischemic pre-condition of an extremity (IPC) induces systemic vasodilatory effects. ► The effects of IPC were evaluated on cyclists under normoxic and hypoxic conditions. ► IPC profoundly blunted the hy...

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Published inRespiratory physiology & neurobiology Vol. 179; no. 2; pp. 248 - 253
Main Authors Foster, Gary P, Westerdahl, Daniel E, Foster, Laura A, Hsu, Jeffrey V, Anholm, James D
Format Journal Article
LanguageEnglish
Published Amsterdam Elsevier B.V 15.12.2011
Elsevier
Subjects
Adult
Biological and medical sciences
Blood Pressure - physiology
Cross-Over Studies
Echocardiography, Doppler, Color
Exercise - physiology
Female
Fundamental and applied biological sciences. Psychology
Humans
Hypoxia
Hypoxia - physiopathology
Ischemic pre-conditioning
Ischemic Preconditioning
Leg - blood supply
Male
Medical Education
Middle Aged
Pulmonary Artery - physiology
Pulmonary pressure
Pulmonary/Respiratory
Vertebrates: respiratory system
Ischemic pre-conditioning
Hypoxia
Pulmonary pressure
Oxygen
Lung
Respiratory system
Pressure
Pulmonary artery
Vertebrata
Mammalia
Pulmonary vessel
Blood vessel
Circulatory system
Conditioning
Preconditioning
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Summary:Highlights ► Hypoxic increases in pulmonary pressures are attributed to local vasoconstriction. ► Ischemic pre-condition of an extremity (IPC) induces systemic vasodilatory effects. ► The effects of IPC were evaluated on cyclists under normoxic and hypoxic conditions. ► IPC profoundly blunted the hypoxic increase of pulmonary artery systolic pressure.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-News-1
ObjectType-Feature-3
content type line 23
ISSN:1569-9048
1878-1519
DOI:10.1016/j.resp.2011.09.001