Molecular signatures database (MSigDB) 3.0

Motivation: Well-annotated gene sets representing the universe of the biological processes are critical for meaningful and insightful interpretation of large-scale genomic data. The Molecular Signatures Database (MSigDB) is one of the most widely used repositories of such sets. Results: We report th...

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Bibliographic Details
Published inBioinformatics (Oxford, England) Vol. 27; no. 12; pp. 1739 - 1740
Main Authors Liberzon, Arthur, Subramanian, Aravind, Pinchback, Reid, Thorvaldsdóttir, Helga, Tamayo, Pablo, Mesirov, Jill P.
Format Journal Article
LanguageEnglish
Published Oxford Oxford University Press 15.06.2011
Subjects
Applications Note
Biological and medical sciences
Databases, Genetic
Fundamental and applied biological sciences. Psychology
General aspects
Genomics
Internet
Mathematics in biology. Statistical analysis. Models. Metrology. Data processing in biology (general aspects)
Molecular Sequence Annotation
Database
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Summary:Motivation: Well-annotated gene sets representing the universe of the biological processes are critical for meaningful and insightful interpretation of large-scale genomic data. The Molecular Signatures Database (MSigDB) is one of the most widely used repositories of such sets. Results: We report the availability of a new version of the database, MSigDB 3.0, with over 6700 gene sets, a complete revision of the collection of canonical pathways and experimental signatures from publications, enhanced annotations and upgrades to the web site. Availability and Implementation: MSigDB is freely available for non-commercial use at http://www.broadinstitute.org/msigdb. Contact:  gsea@broadinstitute.org
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Associate Editor: Alex Bateman
ISSN:1367-4803
1367-4811
1367-4811
DOI:10.1093/bioinformatics/btr260