Ptychographic electron microscopy using high-angle dark-field scattering for sub-nanometre resolution imaging

• Published in: Nature communications Vol. 3; no. 1; p. 730
• Main Authors: Humphry, M.J., Kraus, B., Hurst, A.C., Maiden, A.M., Rodenburg, J.M.
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 06.03.2012; Nature Publishing Group; Nature Pub. Group
• Subjects: 639/624/1107/510; Humanities and Social Sciences; multidisciplinary; Science; Science (multidisciplinary)
• ISSN: 2041-1723; 2041-1723
• DOI: 10.1038/ncomms1733

Diffractive imaging, in which image-forming optics are replaced by an inverse computation using scattered intensity data, could, in principle, realize wavelength-scale resolution in a transmission electron microscope. However, to date all implementations of this approach have suffered from various experimental restrictions. Here we demonstrate a form of diffractive imaging that unshackles the image formation process from the constraints of electron optics, improving resolution over that of the lens used by a factor of five and showing for the first time that it is possible to recover the complex exit wave (in modulus and phase) at atomic resolution, over an unlimited field of view, using low-energy (30 keV) electrons. Our method, called electron ptychography, has no fundamental experimental boundaries: further development of this proof-of-principle could revolutionize sub-atomic scale transmission imaging. Diffractive imaging can deliver wavelength-scale resolution with X-rays, although its use with electrons is hampered by experimental constraints. By applying ptychographic methods to transmission electron microscopy, Humphry et al . demonstrate sub-nanometre resolution using low-energy electrons.