The incorporation of phosphorylated chitosan/amorphous calcium phosphate nanocomplex into an experimental composite resin

• Published in: Dental Materials Journal Vol. 40; no. 2; pp. 422 - 430
• Main Authors: NIU, Ju, LI, Di, ZHOU, Zeying, ZHANG, Jingyue, LIU, Dandan, ZHAO, Wendi, ZHAO, Chengji, LIU, Xiaoqiu
• Format: Journal Article
• Language: English
• Published: Japan The Japanese Society for Dental Materials and Devices 25.03.2021; Japan Science and Technology Agency
• Subjects: Amorphous calcium phosphate; Apatite; Calcium; Calcium Phosphates; Chemical properties; Chitosan; Composite materials; Composite resin; Composite Resins; Contact angle; Demineralizing; Dental materials; Dental restorative materials; Dentin; Humans; Mechanical properties; Remineralization; Resins; Saline solutions; Tooth Remineralization; Dentin; Composite resin; Amorphous calcium phosphate; Remineralization
• ISSN: 0287-4547; 1881-1361; 1881-1361
• DOI: 10.4012/dmj.2019-427

This study evaluated the effect of incorporating phosphorylated chitosan/amorphous calcium phosphate nanocomplex (Pchi/ACP) into an experimental light-cure composite resin on mechanical-chemical properties and human dentin remineralization. The results showed that the mechanical strength and contact angles of the resins decreased with the increase incorporation of Pchi/ACP. Release concentrations of calcium in saline solution were measured at different time points, showing the incorporation of Pchi/ACP significantly increased calcium release within 14 days, and kept steady thereafter. Finally, the demineralized dentin slabs treated with our resins for four weeks were characterized by SEM-EDS. Various amounts of apatite were formed on the dentin slabs which were treated with the resins containing Pchi/ACP, whereas no apatite was formed without Pchi/ACP. In conclusion, the Pchi/ACP-incorporating composite resin can be a promising dental material due to its favorable mechanical and remineralization properties.