Liver transplantation for recurrent posthepatectomy malignant hepatic angiomyolipoma:A case report

Hepatic angiomyolipomas(AMLs) are typically benign tumors containing varying amounts of smooth musclecells, adipose tissue, and vessels, and are commonly found in the kidney and occasionally in the liver. The preoperative diagnosis of hepatic AML is primarily made from imaging and fine-needle aspira...

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Published inWorld journal of gastroenterology : WJG Vol. 21; no. 12; pp. 3755 - 3758
Main Authors Wang, Wen-Tao, Li, Zi-Qiang, Zhang, Gui-Hui, Guo, Yuan, Teng, Mu-Jian
Format Journal Article
LanguageEnglish
Published United States Baishideng Publishing Group Inc 28.03.2015
Subjects
Adult
Angiomyolipoma - chemistry
Angiomyolipoma - pathology
Angiomyolipoma - surgery
Angiomyolipoma;Hepatectomy;Malignant;Liver
Biomarkers, Tumor - analysis
Biopsy
Case Report
Female
Hepatectomy
Humans
Immunohistochemistry
Liver Neoplasms - chemistry
Liver Neoplasms - pathology
Liver Neoplasms - surgery
Liver Transplantation
Magnetic Resonance Imaging
Neoplasm Recurrence, Local
Reoperation
Time Factors
Tomography, X-Ray Computed
transpl
Treatment Outcome
Recurrence
Angiomyolipoma
Malignant
Hepatectomy
Liver transplantation
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Summary:Hepatic angiomyolipomas(AMLs) are typically benign tumors containing varying amounts of smooth musclecells, adipose tissue, and vessels, and are commonly found in the kidney and occasionally in the liver. The preoperative diagnosis of hepatic AML is primarily made from imaging and fine-needle aspiration biopsy results, though limited experience for such diagnoses can result in misdiagnosis. Some uncommon features of hepatic AML have been reported in the literature without an objective or qualitative consensus. As the majority of cases are benign, conservative treatment of AMLs is recommended. However, in rare cases, liver transplantation has been implemented. Only five cases of malignant hepatic AML have been reported. We report a rare case of recurrent posthepatectomy malignant hepatic AML that was misdiagnosed as liver cancer in a 37-year-old woman, which was treated by liver transplantation. The imaging and pathologic findings are presented in order to provide a more concise description to aid in future diagnoses.
Bibliography:Angiomyolipoma;Hepatectomy;Malignant;Liver transpl
Hepatic angiomyolipomas(AMLs) are typically benign tumors containing varying amounts of smooth musclecells, adipose tissue, and vessels, and are commonly found in the kidney and occasionally in the liver. The preoperative diagnosis of hepatic AML is primarily made from imaging and fine-needle aspiration biopsy results, though limited experience for such diagnoses can result in misdiagnosis. Some uncommon features of hepatic AML have been reported in the literature without an objective or qualitative consensus. As the majority of cases are benign, conservative treatment of AMLs is recommended. However, in rare cases, liver transplantation has been implemented. Only five cases of malignant hepatic AML have been reported. We report a rare case of recurrent posthepatectomy malignant hepatic AML that was misdiagnosed as liver cancer in a 37-year-old woman, which was treated by liver transplantation. The imaging and pathologic findings are presented in order to provide a more concise description to aid in future diagnoses.
Wen-Tao Wang;Zi-Qiang Li;Gui-Hui Zhang;Yuan Guo;Mu-Jian Teng;Department of Hepatobiliary Surgery, Shandong Provincial Qianfoshan Hospital, Shandong University
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Correspondence to: Yuan Guo, MD, Department of Hepatobiliary Surgery, Shandong Provincial Qianfoshan Hospital, Shandong University, 27 Shanda Nanlu, Jinan 250014, Shandong Province, China. guoyuan@sdhospital.com.cn
Telephone: +86-531-89268149 Fax: +86-531-89268356
Author contributions: Wang WT and Li ZQ contributed equally to this work; Zhang GH conducted the pathologic analysis; Wang WT wrote the manuscript; Li ZQ, Guo Y and Teng MJ revised the manuscript.
ISSN:1007-9327
2219-2840
DOI:10.3748/wjg.v21.i12.3755