A normative study of total scores of the CERAD neuropsychological assessment battery in an educationally diverse elderly population

• Published in: International psychogeriatrics Vol. 26; no. 11; pp. 1897 - 1904
• Main Authors: Han, Ji Young, Seo, Eun Hyun, Yi, Dahyun, Sohn, Bo Kyung, Choe, Young Min, Byun, Min Soo, Choi, Hyo Jung, Kim, Shin Gyeom, Park, Shin Young, Kim, Jee Wook, Youn, Jong Chul, Jhoo, Jin Hyeong, Lee, Jung Hie, Kim, Ki Woong, Woo, Jong Inn, Lee, Dong Young
• Format: Journal Article
• Language: English
• Published: Cambridge, UK Cambridge University Press 01.11.2014
• Subjects: Ability tests; Age; Age Factors; Aged; Aged, 80 and over; Alzheimer Disease - diagnosis; Alzheimer's disease; Biological and medical sciences; Educational attainment; Educational Status; Female; Gender; Geriatrics; Humans; Male; Medical sciences; Middle Aged; Neuropsychological Tests - standards; Neuropsychological Tests - statistics & numerical data; Older people; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Reproducibility of Results; Sex Factors; CERAD neuropsychological battery; total score; education; gender; norms; age; Human; Sex; Neuropsychological test; Psychometrics; Gender; Elderly; Age
• ISSN: 1041-6102; 1741-203X
• DOI: 10.1017/S1041610214001379

This study aimed to investigate the influences of age, education, and gender on the two total scores (TS-I and TS-II) of the Consortium to Establish a Registry for Alzheimer's Disease Neuropsychological assessment battery (CERAD-NP) and to provide normative information based on an analysis for a large number of elderly persons with a wide range of educational levels. In the study, 1,987 community-dwelling healthy volunteers (620 males and 1,367 females; 50-90 years of age; and zero to 25 years of education) were included. People with serious neurological, medical, and psychiatric disorders (including dementia) were excluded. All participants underwent the CERAD-NP assessment. TS-I was generated by summing raw scores from the CERAD-NP subtests, excluding Mini-Mental State Examination and Constructional Praxis (CP) recall subtests. TS-II was calculated by adding CP recall score to TS-I. Both TS-I and TS-II were significantly influenced by demographic variables. Education accounted for the greatest proportion of score variance. Interaction effect between age and gender was found. Based on the results obtained, normative data of the CERAD-NP total scores were stratified by age (six overlapping tables), education (four strata), and gender. The normative information will be very useful for better interpretation of the CERAD-NP total scores in various clinical and research settings and for comparing individuals' performance of the battery across countries.