Dietary exposure to inorganic arsenic of the Hong Kong population: Results of the first Hong Kong Total Diet Study

• Published in: Food and chemical toxicology Vol. 51; pp. 379 - 385
• Main Authors: Wong, Waiky W.K., Chung, Stephen W.C., Chan, Benny T.P., Ho, Y.Y., Xiao, Ying
• Format: Journal Article
• Language: English
• Published: Oxford Elsevier Ltd 01.01.2013; Elsevier
• Subjects: Adult; adults; Aged; Aged, 80 and over; arsenic; Arsenic - analysis; Arsenic - toxicity; arsenites; Biological and medical sciences; body weight; carcinogenicity; carcinogens; Diet; Dietary exposure; Edible Grain; Environmental Exposure - analysis; Female; Food Contamination - analysis; grains; Hong Kong; Humans; Inorganic arsenic; Male; mass spectrometry; Medical sciences; Middle Aged; Oryza; people; risk; Total diet; Total Diet Study; Toxicology; Vegetables; Young Adult; China; Hong Kong; Asia; China, People's Rep., Hong Kong; Inorganic arsenic; Total diet; Dietary exposure; Human; Nutrition; Diet; Arsenic compound; Exposure; Feeding
• ISSN: 0278-6915; 1873-6351
• DOI: 10.1016/j.fct.2012.10.010

► Mean and 95th percentile of inorganic arsenic exposures of the population were 0.22 and 0.38μg/kg bw/day, respectively. ► Mean inorganic arsenic exposure of various age-gender population groups ranged from 0.19 to 0.26μg/kg bw/day. ► Inorganic arsenic exposure (95th percentile) of various age-gender population groups ranged from 0.33 to 0.46μg/kg bw/day. ► The main dietary source of inorganic arsenic was “cereals and their products”, particularly rice. Inorganic arsenic, a human carcinogen, can be found in the environment and food. In the first Hong Kong Total Diet Study, the dietary exposure of the Hong Kong people, including various age-gender subgroups, to inorganic arsenic was estimated for assessing the associated health risk. Food samples, which represented the Hong Kong people’s diet, were collected and prepared “as consumed” for analysis. Concentrations of inorganic arsenic, as sum of arsenite (As(III)) and arsenate (As(V)) were determined in 600 composite samples by using inductively coupled plasma mass spectrometry. The dietary exposures were estimated by combining the analytical results with the local food consumption data of the adult population. The mean and 95th percentile of inorganic arsenic exposures of the Hong Kong people were 0.22 and 0.38μg/kg body weight (bw)/day, respectively. Among the 12 age-gender subgroups, the respective exposures ranged from 0.19 to 0.26μg/kg bw/day and from 0.33 to 0.46μg/kg bw/day. The main food category that contributed inorganic arsenic was “cereals and their products” (53.5% of the total exposure), particularly rice. Having considered the carcinogenic risk of inorganic arsenic to humans, it is suggested that efforts should be made to reduce the inorganic arsenic exposure of the Hong Kong population.