Multiple Myeloma in a Young Adult with Renal Involvement
Multiple myeloma (MM) results from malignant plasma cell disorder. It represents approximately 10% of hematological malignancies and it is typically diagnosed in the elderly with a median age of 70 years and has a steep increase in incidence with advancing age. N Engl J Med. 2004, 1860; Clin Interv...
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Published in | Clinical case reports Vol. 11; no. 2; pp. e6986 - n/a |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
England
John Wiley & Sons, Inc
01.02.2023
John Wiley and Sons Inc Wiley |
Subjects | |
Online Access | Get full text |
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Summary: | Multiple myeloma (MM) results from malignant plasma cell disorder. It represents approximately 10% of hematological malignancies and it is typically diagnosed in the elderly with a median age of 70 years and has a steep increase in incidence with advancing age. N Engl J Med. 2004, 1860; Clin Interv Aging. 2020, 619. The incidence of MM has been increasing over time, mostly due to population aging. Mayo Clin Proc. 2010, 225 However, certain MMs are diagnosed at young age even under 40 years old (2%). Leuk Lymphoma. 1998, 493; Blood. 2010, 5501. We report a case of a MM in a thirty‐four‐year‐old woman whose circumstance of discovery was acute kidney failure.
(A)Trichrome stain: Intratubular polychromatophilic cylinder with cellular reaction all around (×200). (B) Trichrome stain: Presence of giant cells (×400). (C) Trichrome stain: Optically normal glomeruli (×200). (D) Direct Immunofluorescence: Absence of Ig deposits but presence of lambda on tubular basement membranes and cylinders. |
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Bibliography: | ObjectType-Case Study-2 SourceType-Scholarly Journals-1 content type line 23 ObjectType-Report-1 |
ISSN: | 2050-0904 2050-0904 |
DOI: | 10.1002/ccr3.6986 |