The protective effects of green tea extract against L-arginine toxicity to cultured human mesangial cells

• Published in: Journal of Korean medical science Vol. 24 Suppl; no. Suppl 1; pp. S204 - S209
• Main Authors: Shin, Byung Chul, Ryu, Hyun Ho, Chung, Jong Hoon, Lee, Byoung Rai, Kim, Hyun Lee
• Format: Journal Article
• Language: English
• Published: Korea (South) The Korean Academy of Medical Sciences 01.01.2009; 대한의학회
• Subjects: Antioxidants - metabolism; Arginine - metabolism; Arginine - pharmacology; Arginine - toxicity; Cell Line; Cell Proliferation; Cell Survival; Flavonoids - metabolism; Glomerular Mesangium - cytology; Glomerular Mesangium - metabolism; Humans; Mesangial Cells - cytology; Mesangial Cells - metabolism; Nitric Oxide - chemistry; Nitric Oxide - metabolism; Nitric Oxide Synthase Type II - metabolism; Original; Phenols - metabolism; Polyphenols; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger - metabolism; Tea; 의학일반; Polyphenols; Green Tea Extract; Nitric Oxide; Arginine

The aim of this study was to investigate whether green tea extract (GTE) has the protective effects on excess L-arginine induced toxicity in human mesangial cell. Human mesangial cells treated with L-arginine were cultured on Dulbecco's modified eagle medium in the presence and absence of induc...