Mass Spectrometry Applications in Biomedical Research

• Published in: BioMed research international Vol. 2015; pp. 827370 - 2
• Main Authors: Che, Fa-Yun, Deng, Hai-Teng, Ding, Shi-Jian
• Format: Journal Article
• Language: English
• Published: United States Hindawi Publishing Corporation 01.01.2015; John Wiley & Sons, Inc; Hindawi Limited
• Subjects: Biomarkers; Biomedical Research; Deoxyribonucleic acid; Diabetes; DNA; DNA methylation; Gastric cancer; Humans; Ligands; Mass Spectrometry; Medical research; Medicine, Experimental; Methods; Ovarian cancer; Proteins; Proteomics; Scientific imaging; Studies; United States
• ISSN: 2314-6133; 2314-6141
• DOI: 10.1155/2015/827370

Fa-Yun Che 1 and Hai-Teng Deng 2 and Shi-Jian Ding 3 1, Department of Pathology, Albert Einstein College of Medicine, Bronx, NY 10461, USA 2, School of Life Sciences, Tsinghua University, Beijing, China 3, Diabetes and Obesity Research Center, Sanford-Burnham Medical Research Institute at Lake Nona, Orlando, FL 32827, USA Received 5 April 2015; Accepted 5 April 2015; 21 May 2015 This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. In another quantitative proteomic work performed by Q. Xiong et al., tandem mass tag (TMT) labeling approach was employed to comprehensively compare the differential expression of proteins in receptor activator of nuclear factor-κB ligand- (RANKL-) induced osteoclasts in the presence and absence of estrogen.