Microbiological and clinical characteristics in acute bacterial prostatitis according to lower urinary tract manipulation procedure

• Published in: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy Vol. 20; no. 1; pp. 38 - 42
• Main Authors: Kim, Sang Hoon, Ha, U-Syn, Yoon, Byung Il, Kim, Sun Wook, Sohn, Dong Wan, Kim, Hyun Woo, Cho, Su Yeon, Cho, Yong-Hyun
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 01.01.2014
• Subjects: Acute bacterial prostatitis; Acute Disease; Anti-Bacterial Agents - therapeutic use; Bacterial Infections - drug therapy; Bacterial Infections - microbiology; Hematology, Oncology and Palliative Medicine; Humans; Male; Manipulation; Microbiology; Middle Aged; Prostatitis - drug therapy; Prostatitis - microbiology; Retrospective Studies; Susceptibility; Urinary Tract - drug effects; Urinary Tract - microbiology; Microbiology; Susceptibility; Manipulation; Acute bacterial prostatitis
• ISSN: 1341-321X; 1437-7780
• DOI: 10.1016/j.jiac.2013.11.004

Abstract We conducted a retrospective analysis of acute bacterial prostatitis (ABP) secondary to manipulation to document clinical features, management and microbiology based on the route of prior manipulation, which can be divided into two subgroups: transrectal and transurethral procedure. The medical records of 158 cases compatible with a confirmed diagnosis of ABP secondary to manipulation from 7 urological centers between 2001 and 2012 were reviewed. When subcategorized according to route of prior manipulation of the lower urinary tract, there were distinct differences between transrectal and transurethral manipulation group with regard to clinical and microbiological features. Escherichia coli was the most common causative bacterium in both groups, but Pseudomonas spp. were much more dominant pathogens in the group by transurethral manipulation than transrectal manipulation group. The susceptibilities to second-, third- and fourth-generation cephalosporins, amikacin, carbapenem and aztreonam were shown to be very low in the transurethral manipulation group. Therefore, it will take account the difference in antibiotic selection in the patients with ABP secondary to manipulation according to the manipulation route.