PREOPERATIVE PIROXICAM FOR POSTOPERATIVE ANALGESIA IN DENTAL SURGERY

• Published in: British journal of anaesthesia : BJA Vol. 65; no. 4; pp. 500 - 503
• Main Authors: HUTCHISON, G.L., CROFTS, S.L., GRAY, I.G.
• Format: Journal Article
• Language: English
• Published: Oxford Elsevier Ltd 01.10.1990; Oxford University Press
• Subjects: Acetaminophen - administration & dosage; Adult; Anaesthesia: dental; Analgesia: postoperative; Analgesics; Analgesics: piroxicam; Anesthesia Recovery Period; Anesthesia, Dental; Biological and medical sciences; Female; Humans; Male; Medical sciences; Neuropharmacology; Opium - administration & dosage; Pain, Postoperative - drug therapy; Pain, Postoperative - prevention & control; Pharmacology. Drug treatments; Piroxicam - therapeutic use; Premedication; Tooth Extraction; Anaesthesia: dental; Analgesics: piroxicam; Analgesia: postoperative; Non steroidal antiinflammatory agent; Human; Postoperative; Chemotherapy; Pain; Treatment; Stomatology; Surgery; Tooth; Preoperative; Third molar tooth
• ISSN: 0007-0912; 1471-6771
• DOI: 10.1093/bja/65.4.500

Fifty patients were allocated randomly to receive placebo or piroxicam 40 mg, 2.5 h before surgical removal of lower third molars under general anaesthesia. A significantly greater number of patients in the piroxicam group did not require opioid analgesia after operation (P < 0.05). The piroxicam group also required fewer doses of paracetamol in the first 24 h after recovery from anaesthesia (P < 0.05), and the time from recovery to first postoperative analgesia was longer in those patients who had received piroxicam (P < 0.05). Piroxicam did not significantly prolong the duration of recovery from anaesthesia.