Preparation of Polyvinylidene Fluoride-Gold Nanoparticles Electrospinning Nanofiber Membranes

In this work, gold nanoparticles (AuNPs) and curcumin drug were incorporated in polyvinylidene fluoride (PVDF) nanofibers by electrospinning as a novel tissue engineering scaffold in nerve regeneration. The influence of AuNPs on the morphology, crystallinity, and drug release behavior of nanofiber m...

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Published inBioengineering (Basel) Vol. 9; no. 4; p. 130
Main Authors Ge, Xuemei, Wu, Shang, Shen, Wen, Chen, Lijuan, Zheng, Yan, Ao, Fen, Ning, Yuanlan, Mao, Yueyang, Chen, Zhong
Format Journal Article
LanguageEnglish
Published Switzerland MDPI AG 24.03.2022
MDPI
Subjects
Biocompatibility
Bioengineering
Chloride
Curcumin
Electrospinning
Ethanol
Extracellular matrix
Fluorides
Gold
gold nanoparticles
Membranes
Morphology
Nanofibers
Nanoparticles
nerve regeneration
Nerves
Peptides
Polymers
polyvinylidene fluoride
Polyvinylidene fluorides
Potassium
Reagents
Regeneration
Scanning electron microscopy
Sodium
Tissue engineering
Beijing China
China
Japan
nerve regeneration
electrospinning
gold nanoparticles
polyvinylidene fluoride
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Summary:In this work, gold nanoparticles (AuNPs) and curcumin drug were incorporated in polyvinylidene fluoride (PVDF) nanofibers by electrospinning as a novel tissue engineering scaffold in nerve regeneration. The influence of AuNPs on the morphology, crystallinity, and drug release behavior of nanofiber membranes was characterized. A successful composite nanofiber membrane sample was observed by scanning electron microscopy (SEM). The addition of AuNPs showed the improved as well as prolonged cumulative release of the drug. The results indicated that PVDF-AuNPs nanofiber membrane could potentially be applied for nerve regeneration.
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ISSN:2306-5354
2306-5354
DOI:10.3390/bioengineering9040130