Customized patterned substrates for highly versatile correlative light-scanning electron microscopy

• Published in: Scientific reports Vol. 4; no. 1; p. 7033
• Main Authors: Benedetti, Lorena, Sogne, Elisa, Rodighiero, Simona, Marchesi, Davide, Milani, Paolo, Francolini, Maura
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 13.11.2014; Nature Publishing Group
• Subjects: 13; 14/19; 14/35; 14/63; 147/135; 631/1647/245/2225; 631/1647/328/1649; 631/1647/328/1978; 639/301/930/2735; Electron microscopes; Electron microscopy; Humanities and Social Sciences; multidisciplinary; Scanning electron microscopy; Science

Correlative light electron microscopy (CLEM) combines the advantages of light and electron microscopy, thus making it possible to follow dynamic events in living cells at nanometre resolution. Various CLEM approaches and devices have been developed, each of which has its own advantages and technical...