In Vivo and Real-time Monitoring of Secondary Metabolites of Living Organisms by Mass Spectrometry

Secondary metabolites are compounds that are important for the survival and propagation of animals and plants. Our current understanding on the roles and secretion mechanism of secondary metabolites is limited by the existing techniques that typically cannot provide transient and dynamic information...

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Bibliographic Details
Published inScientific reports Vol. 3; no. 1; p. 2104
Main Authors Hu, Bin, Wang, Lei, Ye, Wen-Cai, Yao, Zhong-Ping
Format Journal Article
LanguageEnglish
Published London Nature Publishing Group UK 01.07.2013
Nature Publishing Group
Subjects
631/1647/2196/2197
631/92/349
639/638/11/296
639/638/11/872
Alkaloids
Animals
Aquatic life
Humanities and Social Sciences
Information processing
Ionization
Mass spectrometry
Mass Spectrometry - methods
Mass spectroscopy
Metabolites
multidisciplinary
Plants
Propagation
Sampling methods
Science
Scientific imaging
Scorpion Venoms - chemistry
Scorpion Venoms - toxicity
Scorpions
Secondary metabolites
Secretion
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Summary:Secondary metabolites are compounds that are important for the survival and propagation of animals and plants. Our current understanding on the roles and secretion mechanism of secondary metabolites is limited by the existing techniques that typically cannot provide transient and dynamic information about the metabolic processes. In this manuscript, by detecting venoms secreted by living scorpion and toad upon attack and variation of alkaloids in living Catharanthus roseus upon stimulation, which represent three different sampling methods for living organisms, we demonstrated that in vivo and real-time monitoring of secondary metabolites released from living animals and plants could be readily achieved by using field-induced direct ionization mass spectrometry.
ISSN:2045-2322
2045-2322
DOI:10.1038/srep02104