Broadband photon pair generation in green fluorescent proteins through spontaneous four-wave mixing

• Published in: Scientific reports Vol. 6; no. 1; p. 24344
• Main Authors: Shi, Siyuan, Thomas, Abu, Corzo, Neil V., Kumar, Prem, Huang, Yuping, Lee, Kim Fook
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 14.04.2016; Nature Publishing Group
• Subjects: 639/624; 639/624/399; 639/766/483; Biomimetics; Fluorophores; Genetic engineering; Green Fluorescent Proteins - metabolism; Humanities and Social Sciences; Information processing; Luminescent Agents - metabolism; multidisciplinary; Optical Phenomena; Photons; Proteins; Quantum theory; Science
• ISSN: 2045-2322; 2045-2322
• DOI: 10.1038/srep24344

Recent studies in quantum biology suggest that quantum mechanics help us to explore quantum processes in biological system. Here, we demonstrate generation of photon pairs through spontaneous four-wave mixing process in naturally occurring fluorescent proteins. We develop a general empirical method for analyzing the relative strength of nonlinear optical interaction processes in five different organic fluorophores. Our results indicate that the generation of photon pairs in green fluorescent proteins is subject to less background noises than in other fluorophores, leading to a coincidence-to-accidental ratio ~145. As such proteins can be genetically engineered and fused to many biological cells, our experiment enables a new platform for quantum information processing in a biological environment such as biomimetic quantum networks and quantum sensors.