Prognosis Risk of Urosepsis in Critical Care Medicine: A Prospective Observational Study

• Published in: BioMed research international Vol. 2016; no. 2016; pp. 1 - 5
• Main Authors: Zhou, Li-Xin, Li, Yi-Nan, Yu, Tie-Ou, Qiang, Xin-Hua
• Format: Journal Article
• Language: English
• Published: Cairo, Egypt Hindawi Publishing Corporation 01.01.2016; Hindawi Limited
• Subjects: Adult; Age; Aged; Biomedical research; Blood pressure; Disease; Enterococcus; Enterococcus - pathogenicity; Escherichia coli; Escherichia coli - pathogenicity; Female; Gender; Hospitals; Humans; Infections; Intensive Care Units; Klebsiella; Klebsiella - pathogenicity; Male; Medical diagnosis; Medicine; Middle Aged; Mortality; Multiple Organ Failure - microbiology; Multiple Organ Failure - pathology; Multivariate analysis; Physiology; Poisoning; Prognosis; Proteus - pathogenicity; Pseudomonas aeruginosa; Pseudomonas aeruginosa - pathogenicity; Risk Factors; Sepsis; Sepsis - microbiology; Sepsis - pathology; Surgery; Urinary Tract Infections - microbiology; Urinary Tract Infections - pathology; Urogenital system
• ISSN: 2314-6133; 2314-6141
• DOI: 10.1155/2016/9028924

This study aimed to investigate the clinical features of urosepsis and to raise awareness of this problem. Of the 112 sepsis patients enrolled, 36 were identified as having urosepsis. The bacteria involved in the infection leading to urosepsis included Escherichia coli, Proteus species, Enterococcus species, Klebsiella species, other Gram-positive cocci, and Pseudomonas aeruginosa. Although the organ/system dysfunction appeared earlier in the urosepsis patients than in the other sepsis patients ( 4.7 ± 2.4 versus 7.2 ± 4.5 hours, P < 0.001 ), the urosepsis patients presented with a better prognosis and lower 28-day mortality rate than the others (6% versus 37%). In the multivariate analysis, the type of sepsis (urosepsis, OR = 0.019, 95% CI = 0.001, 0.335, P = 0.007 ) and SOFA score (OR = 1.896, 95% CI = 1.012, 3.554, P = 0.046 ) remained significantly associated with the survival. The time of admission to the intensive care unit of 17 patients transferred from the Department of Urinary Surgery was significantly prolonged compared with those transferred from other departments ( 11.6 ± 7.3 versus 7.2 ± 4.9 hours, P < 0.05 ). In conclusion, urosepsis suggested a better prognosis, but attention needs to be paid in clinical practice, especially in urinary surgery.