Synaptic transmission: Spillover at central synapses

Recent studies suggest that transmitter molecules released at central synapses sometimes diffuse long enough distances to activate receptors located outside the synaptic cleft or even in neighboring synapses. This transmitter ‘spillover’ may have important physiological consequences.

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Bibliographic Details
Published inCurrent biology Vol. 8; no. 17; pp. R613 - R615
Main Author Huang, Emily P
Format Journal Article
LanguageEnglish
Published England Elsevier Inc 27.08.1998
Subjects
Animals
Neurotransmitter Agents - physiology
Receptor Cross-Talk
Receptors, Glutamate - physiology
Synaptic Transmission - physiology
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Summary:Recent studies suggest that transmitter molecules released at central synapses sometimes diffuse long enough distances to activate receptors located outside the synaptic cleft or even in neighboring synapses. This transmitter ‘spillover’ may have important physiological consequences.
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ISSN:0960-9822
1879-0445
DOI:10.1016/S0960-9822(98)70389-6