Molecular cloning, expression analysis, and potential food intake attenuation effect of peptide YY in grass carp ( Ctenopharyngodon idellus )

• Published in: General and comparative endocrinology Vol. 187; pp. 66 - 73
• Main Authors: Chen, Yong, Shen, Yubang, Pandit, Narayan Prasad, Fu, Jianjun, Li, Da, Li, Jiale
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 15.06.2013
• Subjects: amino acids; Animals; Carps - genetics; Carps - metabolism; Carps - physiology; central nervous system; Cloning, Molecular; complementary DNA; Ctenopharyngodon idella; Ctenopharyngodon idellus; Eating - genetics; Eating - physiology; embryogenesis; Endocrinology & Metabolism; exons; Food intake; gene expression; genes; introns; juveniles; larvae; messenger RNA; molecular cloning; Ontogeny; Peptide YY; Peptide YY - genetics; Peptide YY - metabolism; phylogeny; Postprandial expression; Postprandial Period - genetics; Postprandial Period - physiology; quantitative polymerase chain reaction; Real-Time Polymerase Chain Reaction; signal peptide; Tissue distribution; vertebrates; Postprandial expression; Peptide YY; Ctenopharyngodon idellus; Ontogeny; Tissue distribution; Food intake
• ISSN: 0016-6480; 1095-6840
• DOI: 10.1016/j.ygcen.2013.03.029

Highlights • We provide evidence for the anorectic actions of PYY in grass carp. • gcPYY is expressed abantantly in the central nervous system of grass carp. • Meal is a major stimulus for gcPYY release. • PYY could have an important role on energy regulation in the early life history of grass carp. • gcPYY(1-36) peptide could be a pharmacological tool to control food intake.