ESTROGEN RECEPTOR BETA TYPE IN THE RAT URINARY BLADDER

• Published in: Archives of andrology Vol. 52; no. 5; pp. 407 - 410
• Main Authors: Eliçevik, M., Horasanli, S., Okaygün, E., Badur, S., Celayir, S.
• Format: Journal Article
• Language: English
• Published: Philadelphia, PA Informa UK Ltd 2006; Taylor & Francis
• Subjects: Animals; Base Sequence; Biological and medical sciences; bladder; Chi-Square Distribution; DNA Primers; estrogen; Estrogen Receptor beta - metabolism; Female; Fundamental and applied biological sciences. Psychology; Gynecology. Andrology. Obstetrics; Male; Male genital diseases; Mammalian male genital system; Medical sciences; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; sex hormone receptor; Urinary Bladder - metabolism; Vertebrates: reproduction; Estrogen receptor; Rat; Rodentia; Estrogen; sex hormone receptor; Male genital system; Ovarian hormone; Vertebrata; Mammalia; Urinary system; Urinary bladder; Animal; bladder; Sex steroid hormone; Hormonal receptor
• ISSN: 0148-5016; 1521-0375
• DOI: 10.1080/01485010600666821

This study was conducted to localize estrogen receptor beta (ERβ) in the rat urinary bladder respect to gender. The bladder dome and trigone of 16 Sprague Dawley rats (Male: 8, Female: 8) were evaluated utilizing the reverse transcriptase-polymerase chain reaction technique (RT-PCR) to detect ERβ signal. Chi square test was used for statistical analysis. ERβ was present in the bladder of 13 rats and absent in 3. The side of expression was bladder trigfone in 13 rats and besides ERβ (M: 1, F: 2) was also present in the bladder dome of 3. The relationship between the distribution of ERβ in the bladder and gender was not different. ERβ is present in the bladder trigone of rats independent of gender. Estrogen action in the bladder trigone is also important in males besides females.