Porcine epidemic diarrhea in China

• Published in: Virus research Vol. 226; pp. 7 - 13
• Main Authors: Wang, Dang, Fang, Liurong, Xiao, Shaobo
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 02.12.2016
• Subjects: Animals; China; China - epidemiology; Coronavirus Infections - veterinary; Diarrhea - veterinary; Disease Outbreaks; Genome, Viral; Genotype; History, 20th Century; Molecular characteristics; Phylogeny; Porcine epidemic diarrhea virus; Porcine epidemic diarrhea virus - classification; Porcine epidemic diarrhea virus - genetics; Prevalence; Prevention; Swine; Swine Diseases - epidemiology; Swine Diseases - history; Swine Diseases - prevention & control; Swine Diseases - virology; Viral Vaccines - immunology; Prevention; Porcine epidemic diarrhea virus; Prevalence; Molecular characteristics; China
• ISSN: 0168-1702; 1872-7492
• DOI: 10.1016/j.virusres.2016.05.026

•Porcine epidemic diarrhea (PED) has become a major threat to the pig farming industry in China.•Epidemic PEDV variants tend to be more pathogenic and cause a high number of pig deaths.•The hypervariability of PEDV makes field pandemics more complex and heterogeneous.•Continuous emergence of PEDV highlights the need for efficient vaccines based on the epidemic PEDV. Porcine epidemic diarrhea (PED) is a contagious intestinal disease caused by Porcine epidemic diarrhea virus (PEDV) that characterized by vomiting, diarrhea, and dehydration. PEDV was first identified in the 1980s in China, and since then, it has become one of the most common viral causes of diarrhea. In October 2010, a large-scale outbreak of PED caused by a PEDV variant occurred in China, resulting in tremendous economic losses. This review presents a comprehensive description of PEDV history, prevalence, molecular features, and prevention and control strategies in China.