Toward understanding the origin and evolution of cellular organisms

In this era of high‐throughput biology, bioinformatics has become a major discipline for making sense out of large‐scale datasets. Bioinformatics is usually considered as a practical field developing databases and software tools for supporting other fields, rather than a fundamental scientific disci...

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Bibliographic Details
Published inProtein science Vol. 28; no. 11; pp. 1947 - 1951
Main Author Kanehisa, Minoru
Format Journal Article
LanguageEnglish
Published Hoboken, USA John Wiley & Sons, Inc 01.11.2019
Wiley Subscription Services, Inc
Subjects
Bioinformatics
Biological evolution
Biology
Computational Biology
Databases, Genetic
Gene sequencing
Genomes
High-Throughput Screening Assays
Humans
KEGG
KEGG MEDICUS
KEGG module
Knowledge bases (artificial intelligence)
pathway mapping
reaction module
Review
Reviews
Software
Software development tools
KEGG
KEGG MEDICUS
reaction module
pathway mapping
KEGG module
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Summary:In this era of high‐throughput biology, bioinformatics has become a major discipline for making sense out of large‐scale datasets. Bioinformatics is usually considered as a practical field developing databases and software tools for supporting other fields, rather than a fundamental scientific discipline for uncovering principles of biology. The KEGG resource that we have been developing is a reference knowledge base for biological interpretation of genome sequences and other high‐throughput data. It is now one of the most utilized biological databases because of its practical values. For me personally, KEGG is a step toward understanding the origin and evolution of cellular organisms.
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Minoru Kanehisa is the winner of the 2019 Carl Branden Award.
ISSN:0961-8368
1469-896X
1469-896X
DOI:10.1002/pro.3715