Parotid gland masses: outcomes in the pediatric age group

• Published in: Journal of Egyptian National Cancer Institute Vol. 35; no. 1; pp. 2 - 12
• Main Authors: Younes, Alaa, Taher, Mohammad Fouad, Sidhom, Iman, Zekri, Wael, Zaky, Iman, Elfendy, Habiba, Taher, Azza Niazy, Khedr, Suzan Adlan, Gamal, Rana, Ahmed, Gehad
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 06.02.2023; Springer; Springer Nature B.V; SpringerOpen
• Subjects: Adenoma, Pleomorphic - pathology; Adenoma, Pleomorphic - surgery; Adjuvant radiotherapy; Adult; Age; Biopsy; Biopsy, Fine-Needle; Cancer therapies; Cellular biology; Child; Dissection; Exocrine glands; Humans; Lymphatic system; Medical prognosis; Medicine; Medicine & Public Health; Metastasis; Mortality; Neck dissection for parotid tumors; Oncology; Oral cancer; Parotid FNAC; Parotid Gland - pathology; Parotid Gland - surgery; Parotid Neoplasms - diagnosis; Parotid Neoplasms - pathology; Parotid Neoplasms - therapy; Parotidectomy; Pathology; Patients; Pediatric parotid tumors; Pediatrics; Radiation therapy; Radiotherapy; Retrospective Studies; Surgery; Survival analysis; Tumors; Egypt; Adjuvant radiotherapy; Pediatric parotid tumors; Parotid FNAC; Parotidectomy; Neck dissection for parotid tumors
• ISSN: 1110-0362; 2589-0409
• DOI: 10.1186/s43046-023-00161-8

Background Childhood parotid neoplasms appear to have different characteristics from adults. This point, in addition to the rarity of these tumors, reflects the challenges faced in diagnosing and treating parotid neoplasms in children. Patients and methods This retrospective study included all children who presented to the Children’s Cancer Hospital Egypt (CCHE, 57357) with parotid masses from January 2008 to December 2020. Results Twenty-one patients were included. Malignant neoplasms were found in 12 (57.1%) of which mucoepidermoid carcinoma was the most common. Benign neoplasms were found in 6 (28.6%) all of them were pleomorphic adenoma, and non-neoplastic lesions were found in 3 (14.3%). Superficial, deep, or total parotidectomy was performed according to the involved lobes. The facial nerve was sacrificed in three cases because of frank invasion by the tumor. Neck dissection was considered in clinically positive lymph nodes and/or T3/4 masses. Complications occurred in 7 (33.3%) all were of the malignant cases. Adjuvant radiotherapy was restricted to high-risk cases (7 cases). Recurrence occurred in two cases, and one patient died of distant metastasis. Fine needle aspiration cytology (FNAC) showed 88.9% sensitivity and 100% specificity for diagnosing malignant neoplasms. The correlation of radiological and pathological staging was fair (66.74% for overall staging). Conclusions Parotidectomy is the backbone treatment for benign and malignant pediatric parotid tumors. Neck nodal dissection should be considered after preoperative FNAC of suspicious nodes. Adjuvant radiotherapy is considered only in high-risk tumors. Preoperative FNAC of parotid masses and clinically suspicious lymph nodes is highly recommended.