Screening and early detection of pancreatic cancer in high risk population

Pancreatic cancer is a serious growing health issue in developed countries.For patients diagnosed with pancreatic cancer,the five year survival rate is below 5%.One major important reason leads to the poor survival rate is lack of early detection of pancreatic cancer.Over 80% of the patients are dia...

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Published inWorld journal of gastroenterology : WJG Vol. 20; no. 9; pp. 2358 - 2364
Main Author Chang, Ming-Chu
Format Journal Article
LanguageEnglish
Published United States Baishideng Publishing Group Co., Limited 07.03.2014
Subjects
cancer
Diagnostic Imaging - methods
Early Detection of Cancer - methods
High
Humans
Pancreatic
Pancreatic Neoplasms - diagnosis
Pancreatic Neoplasms - epidemiology
Pancreatic Neoplasms - therapy
Patient Selection
population
Predictive Value of Tests
Prognosis
risk
Risk Assessment
Risk Factors
screening
Time Factors
Topic Highlight
High risk population
Pancreatic cancer screening
Pancreatic neoplasm
Peutz-Jeghers syndrome
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Summary:Pancreatic cancer is a serious growing health issue in developed countries.For patients diagnosed with pancreatic cancer,the five year survival rate is below 5%.One major important reason leads to the poor survival rate is lack of early detection of pancreatic cancer.Over 80% of the patients are diagnosed in advanced disease stages.Screening for pancreatic cancer is a desirable option for high risk individuals to allow early detection and treatment of curable pancreatic neoplasms at a pre-invasive stage.This article highlights the need,endpoint,population,method,diagnostic yield,and the problems of current screening programs.
Bibliography:Ming-Chu Chang;Jau-Min Wong;Yu-Ting Chang;Department of Internal Medicine, National Taiwan University Hospital,College of Medicine, National Taiwan University
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SourceType-Scholarly Journals-1
ObjectType-Feature-2
ObjectType-Review-3
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Telephone: +886-2-23123456 Fax: +886-2-23633658
Author contributions: Chang MC, Wong JM and Chang YT designed the study; Chang MC and Chang YT wrote the manuscript.
Correspondence to: Yu-Ting Chang, MD, MS, PhD, Department of Internal Medicine, National Taiwan University Hospital, No.7, Chung Shan South Road, Taipei 101, Taiwan. yutingchang@ntu.edu.tw
ISSN:1007-9327
2219-2840
2219-2840
DOI:10.3748/wjg.v20.i9.2358