Assessment of Microbiota Modulation in Poultry to Combat Infectious Diseases

• Published in: Animals (Basel) Vol. 11; no. 3; p. 615
• Main Authors: Montoro-Dasi, Laura, Villagra, Arantxa, de Toro, María, Pérez-Gracia, María Teresa, Vega, Santiago, Marin, Clara
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 26.02.2021; MDPI
• Subjects: 16S rRNA analysis; Age; Animal health; Animal welfare; Antibiotics; Antimicrobial resistance; Bacteria; Biodiversity; Biomarkers; broiler; Composition; Deoxyribonucleic acid; Disease control; DNA; Evaluation; Farm management; Farms; Feeds; Gene amplification; growing period; Infectious diseases; Intensive farming; Intestinal microflora; Microbiota; Poultry; Poultry housing; Public concern; Residential areas; rRNA 16S; Sequence analysis; Statistical analysis; Ventilation; welfare; Spain; 16S rRNA analysis; microbiota; farm management; welfare; broiler; growing period
• ISSN: 2076-2615; 2076-2615
• DOI: 10.3390/ani11030615

Poultry is one of the main agricultural sub-sectors worldwide. However, public concern regarding animal welfare and antimicrobial resistance has risen in recent years. Due to the influence of management practices on microbiota, it might be considered to evaluate poultry welfare and health. Therefore, the objective of this research was to analyse the influence on microbiota balance of broilers under commercial and optimal farm conditions, using 16S rRNA sequencing analysis. The research was performed in two identical poultry houses (commercial vs. optimal). Results showed a higher level of microbiota complexity in the group reared under optimal farm conditions at the end of rearing. Regarding microbiota composition, Firmicutes was the dominant phylum during the entire growing period. However, the second most prevalent phylum was Proteobacteria at the arrival day, and Bacteroidetes from the mid-period onward in both groups. Moreover, the most predominant genera identified were , , , and . In conclusion, it is necessary to optimize farm management as much as possible. Using gut microbiota diversity and composition as biomarkers of animal health could be an important tool for infectious disease control, with the aim of reducing the administration of antibiotics at field level.