Epidemiological studies of migration and environmental risk factors in the inflammatory bowel diseases
Inflammatory bowel diseases(IBD)are idiopathic chronic diseases of the gastrointestinal tract well known to be associated with both genetic and environmental risk factors.Permissive genotypes may manifest into clinical phenotypes under certain environmental influences and these may be best studied f...
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Published in | World journal of gastroenterology : WJG Vol. 20; no. 5; pp. 1238 - 1247 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
United States
Baishideng Publishing Group Co., Limited
07.02.2014
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Subjects | |
Online Access | Get full text |
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Summary: | Inflammatory bowel diseases(IBD)are idiopathic chronic diseases of the gastrointestinal tract well known to be associated with both genetic and environmental risk factors.Permissive genotypes may manifest into clinical phenotypes under certain environmental influences and these may be best studied from migratory studies.Exploring differences between first and second generation migrants may further highlight the contribution of environmental factors towards the development of IBD.There are few opportunities that have been offered so far.We aim to review the available migration studies on IBD,evaluate the known environmental factors associated with IBD,and explore modern migration patterns to identify new opportunities and candidate migrant groups in IBD migration research. |
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Bibliography: | Yanna Ko;Rhys Butcher;Rupert W Leong;Concord Hospital, Gastroenterology and Liver Services and The University of New South Wales ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1 Author contributions: Ko Y contributed to this work, performed the literature review and the literature review, and analysed the data; Leong RW designed the research; Ko Y, Butcher R and Leong RW wrote the paper. Correspondence to: Rupert W Leong, MBBS, MD, FRACP, AGAF, Associate Professor, Concord Hospital, Gastroenterology and Liver Services and The University of New South Wales, Level 1 West Hospital Rd, Concord, Sydney NSW 2139, Australia. rupertleong@outlook.com Telephone: +61-2-97676111 Fax: +61-2-97676767 |
ISSN: | 1007-9327 2219-2840 |
DOI: | 10.3748/wjg.v20.i5.1238 |