Terpinen-4-ol, the Main Bioactive Component of Tea Tree Oil, as an Innovative Antimicrobial Agent against Legionella pneumophila

• Published in: Pathogens (Basel) Vol. 11; no. 6; p. 682
• Main Authors: Mondello, Francesca, Fontana, Stefano, Scaturro, Maria, Girolamo, Antonietta, Colone, Marisa, Stringaro, Annarita, Vito, Maura Di, Ricci, Maria Luisa
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 14.06.2022; MDPI
• Subjects: anti-infective agents; antibacterial activity; antibacterial properties; Antiinfectives and antibacterials; Antimicrobial activity; Antimicrobial agents; Bacterial diseases; Bactericidal activity; bioactive compounds; Cell surface; Contamination; COVID-19; Cytology; Dilution; Disinfection; essential oil; Essential oils; Europe; Legionella pneumophila; Legionnaire's disease; Legionnaires' disease bacterium; Melaleuca alternifolia; Minimum inhibitory concentration; Morphology; pneumonia; Pollution control; Scanning electron microscopy; System effectiveness; tea; tea tree oil; Temperature; Temperature dependence; terpinen-4-ol; Terpinene; trees; Vapors; Warm water; Italy; Europe

Legionella pneumophila (Lp), responsible for a severe pneumonia called Legionnaires’ disease, represents an important health burden in Europe. Prevention and control of Lp contamination in warm water systems is still a great challenge often due to the failure in disinfection procedures. The aim of t...