One-step hysteroscopic removal of sinking submucous myoma in two infertile patients

• Published in: Fertility and sterility Vol. 74; no. 5; pp. 1035 - 1038
• Main Authors: Lin, Bao-Liang, Akiba, Yasuo, Iwata, Yoshiyuki
• Format: Journal Article Conference Proceeding
• Language: English
• Published: New York, NY Elsevier Inc 01.11.2000; Elsevier Science
• Subjects: Adult; Biological and medical sciences; Endoscopy; Female; Gonadotropin-Releasing Hormone - agonists; Humans; Hyponatremia - etiology; Hysteroscopy; Infertility, Female - etiology; Medical sciences; Menorrhagia - etiology; Myoma; Myoma - diagnostic imaging; Myoma - surgery; Postoperative Complications; resectoscopic myomectomy; sinking tumor; submucous myoma; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Surgery of the genital tract and mammary gland; Ultrasonography; Uterine Neoplasms - diagnostic imaging; Uterine Neoplasms - surgery; Myoma; submucous myoma; resectoscopic myomectomy; hysteroscopy; sinking tumor; Human; Hysteroscopy; Myometrium; Intrauterus pressure; Female genital diseases; Case study; Treatment; Uterus; Surgery; Female genital system; Uterine diseases; Female; Tumor
• ISSN: 0015-0282; 1556-5653
• DOI: 10.1016/S0015-0282(00)01548-X

Objective: To report one-step resectoscopic removal of submucous myomas that were pushed back into the muscular layer by increased intrauterine pressure during hysteroscopic procedures. Design: Case report. Setting: Kawasaki Municipal Hospital, Kawasaki, Japan. Patient(s): Two infertile women presenting with menorrhagia in whom submucous myoma with a broad base was diagnosed. Intervention(s): One patient was pretreated with GnRH agonist for 4 months; the other patient did not receive this treatment. Resectoscopic myomectomies were performed under close sonographic monitoring. Main Outcome Measure(s): Clinical symptoms and conception status. Result(s): Tumor sinking occurred during the hysteroscopic procedures, but complete resectoscopic removal of the submucous myomas was achieved under sonographic and hysteroscopic visualization. One patient experienced hyponatremia but recovered after conservative treatment. Both patients conceived after myoma removal. Conclusion(s): Sinking myomas, which may cause infertility, can be removed with a one-step hysteroscopic procedure. Sinking of submucous myomas during hysteroscopy might be caused by pretreatment with GnRH agonist and by increased intrauterine pressure during hysteroscopy. We recommend that intrauterine pressure be <45 mmHg, equivalent to hanging a bag of fluid under gravity control 70 cm above the patient’s uterus, at the beginning of operations for sinking myomas.