A comparison of covered and uncovered Wallstents for the management of distal malignant biliary obstruction

• Published in: Gastrointestinal endoscopy Vol. 63; no. 7; pp. 996 - 1000
• Main Authors: Yoon, Won Jae, MD, Lee, Jun Kyu, MD, Lee, Kwang Hyuck, MD, Lee, Woo Jin, MD, Ryu, Ji Kon, MD, Kim, Yong-Tae, MD, Yoon, Yong Bum, MD
• Format: Journal Article
• Language: English
• Published: New York, NY Mosby, Inc 01.06.2006; Elsevier
• Subjects: Bile Duct Neoplasms - complications; Bile Duct Neoplasms - pathology; Bile Ducts, Extrahepatic; Biological and medical sciences; Cholangiocarcinoma - complications; Cholangiocarcinoma - pathology; Common Bile Duct - pathology; Constriction, Pathologic; Digestive system. Abdomen; Endoscopy; Female; Foreign-Body Migration - epidemiology; Gastroenterology and Hepatology; Gastroenterology. Liver. Pancreas. Abdomen; Humans; Investigative techniques, diagnostic techniques (general aspects); Jaundice, Obstructive - therapy; Male; Medical sciences; Metals; Middle Aged; Palliative Care; Pancreatic Neoplasms - complications; Prosthesis Design; Retrospective Studies; Stents - adverse effects; Biliary tract; Comparative study; Malignant tumor
• ISSN: 0016-5107; 1097-6779
• DOI: 10.1016/j.gie.2005.11.054

Background The efficacy and complications of covered self-expandable metal stents (SEMS) remain controversial. Objective We conducted this study to compare the efficacies and complication rates of covered and uncovered SEMS in malignant biliary obstruction. Design Data on patients who underwent endoscopic retrograde biliary drainage using covered or uncovered Wallstents (Boston Scientific, Natick, Mass) for the palliation of unresectable distal malignant biliary obstruction were collected. Stent patency, complications, and causes of stent occlusion were analyzed. Setting We collected the data retrospectively. Patients A total of 77 patients received Wallstents for unresectable distal malignant biliary obstruction. Interventions Endoscopic sphincterotomy was performed, and a Wallstent was deployed after guidewire passage. Polyurethane-covered Wallstents were used in 36 patients and uncovered Wallstents in 41 patients. Results Stent migration occurred in 3 in the covered Wallstent group and in 1 of the uncovered Wallstent group. Cholecystitis occurred in 1 of the covered Wallstent group but in none of the uncovered Wallstent group. Stent occlusion occurred after a mean of 398 days in the covered group and after 319 days in the uncovered Wallstent group ( P > .05). Stent patency rates were 83%, 78%, 67%, and 54% at 100, 200, 300 and 400 days, respectively, in covered group and 83%, 66%, 54%, and 36% in the uncovered group, which was not significantly different. Limitations This study is not a prospective randomized study and sample size is not large. Conclusions Covered Wallstents are safe with acceptable complication rates. However, we found no significant difference between the stent patencies of covered and uncovered Wallstents.