Acute toxicity and responses of antioxidant systems to 1-methyl-3-octylimidazolium bromide at different developmental stages of goldfish
Acute toxicity of 1-methyl-3-octylimidazolium bromide ([C 8 mim]Br) to goldfish at different developmental stages and responses of the antioxidant system in adult goldfish were evaluated in the present study. The results indicate that post-embryonic developmental toxicity of [C 8 mim]Br on goldfish...
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Published in | Ecotoxicology (London) Vol. 21; no. 1; pp. 253 - 259 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
Boston
Springer US
2012
Springer Springer Nature B.V |
Subjects | |
Online Access | Get full text |
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Summary: | Acute toxicity of 1-methyl-3-octylimidazolium bromide ([C
8
mim]Br) to goldfish at different developmental stages and responses of the antioxidant system in adult goldfish were evaluated in the present study. The results indicate that post-embryonic developmental toxicity of [C
8
mim]Br on goldfish is developmental-stage dependent. The juvenile and larva goldfish are more sensitive to [C
8
mim]Br-toxicity than the adult fish. Histological observations in adult goldfish reveal that acute [C
8
mim]Br exposure damages the hepatopancreas, intestines, and kidneys, indicating that these are possible target organs of [C
8
mim]Br toxicity in goldfish. Subsequent biochemical assays in adult goldfish show that [C
8
mim]Br also induces changes in the activities of the superoxide dismutase, catalase, glutathione peroxidase, and glutathione content of fish hepatopancreas. These results suggest that [C
8
mim]Br exposure may induce oxidant stress and lipid peroxidation in hepatopancreas of adult goldfish. In addition, we also find that [C
8
mim]Br causes a remarkable increase in malondialdehyde (MDA) levels in the hepatopancreas of adult goldfish, and thus we think that the MDA level change can be a biomarker of [C
8
mim]Br toxicity in goldfish. The present study indicates that ionic liquids can be a threat to the survival, growth, and development of the fish population once they are accidentally leaked into aquatic ecosystems. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0963-9292 1573-3017 |
DOI: | 10.1007/s10646-011-0785-z |