Study of the Nature of Sympathetic Trunk Nerve Fibers Enhancing Gastric Motility

Stimulation of the sympathetic nerve in the thoracic cavity often does not inhibit, but increases stomach contractions in dogs. Blockade of α- and β-adrenoceptors potentiates this stimulatory effect, while blockade of S 1,2 -receptors localized mainly in smooth muscle cells eliminates it. It is conc...

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Published inBulletin of experimental biology and medicine Vol. 152; no. 3; pp. 283 - 285
Main Authors Sveshnikov, D. S., Smirnov, V. M., Myasnikov, I. L., Kuchuk, A. V.
Format Journal Article
LanguageEnglish
Published Boston Springer US 2012
Springer
Springer Nature B.V
Subjects
Adrenergic Antagonists - administration & dosage
Adrenergic Antagonists - pharmacology
Adrenergic Fibers - physiology
Animals
Biomedical and Life Sciences
Biomedicine
Cell Biology
Dogs
Electric Stimulation
Ergolines
Gastric motility
Gastrointestinal Motility - physiology
Gastrointestinal system
Internal Medicine
Laboratory Medicine
Pathology
Phentolamine - administration & dosage
Phentolamine - pharmacology
Physiology
Propranolol - administration & dosage
Propranolol - pharmacology
Serotonergic Neurons - physiology
Smooth muscle
Stomach
sympathetic nerves
Thorax
serotonergic fi bers
stomach
sympathetic nerve
regulation
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Summary:Stimulation of the sympathetic nerve in the thoracic cavity often does not inhibit, but increases stomach contractions in dogs. Blockade of α- and β-adrenoceptors potentiates this stimulatory effect, while blockade of S 1,2 -receptors localized mainly in smooth muscle cells eliminates it. It is concluded that sympathetic nerve includes serotonergic fi bers stimulating gastric motility.
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ISSN:0007-4888
1573-8221
DOI:10.1007/s10517-012-1508-z