ALBOCYCLINE: STRUCTURE DETERMINATION BY X-RAY CRYSTALLOGRAPHY

The structure and absolute configuration of the macrolide antibiotic albocycline (1a) has been determined by X-ray crystallographic analysis on the derived p-bromobenzoate (1b). The absolute configuration of albocycline is 4R, 7S, 12S, 13R.

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Bibliographic Details
Published inJournal of antibiotics Vol. 35; no. 12; pp. 1658 - 1664
Main Authors THOMAS, RICHARD C., CHIDESTER, CONNIE G.
Format Journal Article
LanguageEnglish
Published Japan JAPAN ANTIBIOTICS RESEARCH ASSOCIATION 01.01.1982
Subjects
Anti-Bacterial Agents
Lactones
Magnetic Resonance Spectroscopy
Models, Molecular
X-Ray Diffraction
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Summary:The structure and absolute configuration of the macrolide antibiotic albocycline (1a) has been determined by X-ray crystallographic analysis on the derived p-bromobenzoate (1b). The absolute configuration of albocycline is 4R, 7S, 12S, 13R.
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ISSN:0021-8820
1881-1469
DOI:10.7164/antibiotics.35.1658