Health-related quality of life after ileoanal pull-through evaluation and assessment of new health status measures

• Published in: Gastroenterology (New York, N.Y. 1943) Vol. 113; no. 1; p. 7
• Main Authors: Provenzale, D, Shearin, M, Phillips-Bute, B G, Drossman, D A, Li, Z, Tillinger, W, Schmitt, C M, Bollinger, R R, Koruda, M J
• Format: Journal Article
• Language: English
• Published: United States 01.07.1997
• Subjects: Adult; Colitis, Ulcerative - psychology; Colitis, Ulcerative - surgery; Evaluation Studies as Topic; Female; Health Status Indicators; Humans; Male; Proctocolectomy, Restorative - psychology; Quality of Life; Sickness Impact Profile; Surveys and Questionnaires
• ISSN: 0016-5085
• DOI: 10.1016/S0016-5085(97)70074-X

Health-related quality of life (HRQL) after proctocolectomy is a critical parameter for management decisions in patients with chronic pancolitis. The aim of this study was to evaluate the HRQL of patients with ileoanal pull-through and to validate new, easy-to-administer HRQL measures. The Sickness Impact Profile (SIP), Short Form 36 (SF-36), Rating Form of Inflammatory Bowel Disease (IBD) Patient Concerns (RFIPC), and the time trade-off (TTO) were used to measure HRQL of pull-through patients. The SF-36 and the RFIPC were validated. HRQL of patients with ileoanal pull-through was better than that of a national sample of patients with IBD (SIP and RFIPC) and similar to that of a normal population (SF-36). Physical and psychosocial subscales of the SF-36 correlated with the SIP, affirming the construct validity of the SF-36. The RFIPC results correlated with the SIP and SF-36 results, suggesting that it is also a valid health status measure for these patients. TTO results correlated with the physical subscales of the SIP and SF-36, reflecting the impact of physical health on this group. HRQL of patients with ileoanal pull-through is excellent. The SF-36 and RFIPC are valid health status measures that can be used by clinicians and researchers in these patients.