Effect of caloric restriction on depression

Recently, most of evidence shows that caloric restriction could induce antidepressant‐like effects in animal model of depression. Based on studies of the brain–gut axis, some signal pathways were common between the control of caloric restriction and depression. However, the specific mechanism of the...

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Published inJournal of cellular and molecular medicine Vol. 22; no. 5; pp. 2528 - 2535
Main Authors Manchishi, Stephen Malunga, Cui, Ran Ji, Zou, Xiao Han, Cheng, Zi Qian, Li, Bing jin
Format Journal Article
LanguageEnglish
Published England John Wiley & Sons, Inc 01.05.2018
John Wiley and Sons Inc
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Abstract Recently, most of evidence shows that caloric restriction could induce antidepressant‐like effects in animal model of depression. Based on studies of the brain–gut axis, some signal pathways were common between the control of caloric restriction and depression. However, the specific mechanism of the antidepressant‐like effects induced by caloric restriction remains unclear. Therefore, in this article, we summarized clinical and experimental studies of caloric restriction on depression. This review may provide a new therapeutic strategy for depression.
AbstractList Recently, most of evidence shows that caloric restriction could induce antidepressant‐like effects in animal model of depression. Based on studies of the brain–gut axis, some signal pathways were common between the control of caloric restriction and depression. However, the specific mechanism of the antidepressant‐like effects induced by caloric restriction remains unclear. Therefore, in this article, we summarized clinical and experimental studies of caloric restriction on depression. This review may provide a new therapeutic strategy for depression.
Abstract Recently, most of evidence shows that caloric restriction could induce antidepressant‐like effects in animal model of depression. Based on studies of the brain–gut axis, some signal pathways were common between the control of caloric restriction and depression. However, the specific mechanism of the antidepressant‐like effects induced by caloric restriction remains unclear. Therefore, in this article, we summarized clinical and experimental studies of caloric restriction on depression. This review may provide a new therapeutic strategy for depression.
Author Zou, Xiao Han
Cheng, Zi Qian
Li, Bing jin
Manchishi, Stephen Malunga
Cui, Ran Ji
AuthorAffiliation 2 Department of Physiology University of Cambridge Cambridge UK
1 Jilin Provincial Key Laboratory on Molecular and Chemical Genetics The Second Hospital of Jilin University Changchun Jilin China
AuthorAffiliation_xml – name: 2 Department of Physiology University of Cambridge Cambridge UK
– name: 1 Jilin Provincial Key Laboratory on Molecular and Chemical Genetics The Second Hospital of Jilin University Changchun Jilin China
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  givenname: Stephen Malunga
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  surname: Cui
  fullname: Cui, Ran Ji
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  givenname: Xiao Han
  surname: Zou
  fullname: Zou, Xiao Han
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  givenname: Zi Qian
  surname: Cheng
  fullname: Cheng, Zi Qian
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  surname: Li
  fullname: Li, Bing jin
  email: libingjin@jlu.edu.cn
  organization: The Second Hospital of Jilin University
BackLink https://www.ncbi.nlm.nih.gov/pubmed/29465826$$D View this record in MEDLINE/PubMed
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Issue 5
Keywords fasting
calorie restriction
BDNF
antidepressant
Language English
License Attribution
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This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
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Snippet Recently, most of evidence shows that caloric restriction could induce antidepressant‐like effects in animal model of depression. Based on studies of the...
Recently, most of evidence shows that caloric restriction could induce antidepressant-like effects in animal model of depression. Based on studies of the...
Abstract Recently, most of evidence shows that caloric restriction could induce antidepressant‐like effects in animal model of depression. Based on studies of...
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SubjectTerms Animal cognition
Animal models
antidepressant
Anxiety
Autophagy
BDNF
calorie restriction
Calories
Cognitive ability
Cytokines
Diet
Dietary restrictions
Disease
Energy
Fasting
Food
Gene expression
Kinases
Ligands
Malnutrition
Mental depression
Mental disorders
Neurogenesis
Neurological disorders
Phosphorylation
Proteins
Psychiatry
Quality of life
Review
Reviews
Weight control
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Title Effect of caloric restriction on depression
URI https://onlinelibrary.wiley.com/doi/abs/10.1111%2Fjcmm.13418
https://www.ncbi.nlm.nih.gov/pubmed/29465826
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Volume 22
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