Effect of caloric restriction on depression

Recently, most of evidence shows that caloric restriction could induce antidepressant‐like effects in animal model of depression. Based on studies of the brain–gut axis, some signal pathways were common between the control of caloric restriction and depression. However, the specific mechanism of the...

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Bibliographic Details
Published inJournal of cellular and molecular medicine Vol. 22; no. 5; pp. 2528 - 2535
Main Authors Manchishi, Stephen Malunga, Cui, Ran Ji, Zou, Xiao Han, Cheng, Zi Qian, Li, Bing jin
Format Journal Article
LanguageEnglish
Published England John Wiley & Sons, Inc 01.05.2018
John Wiley and Sons Inc
Subjects
Animal cognition
Animal models
antidepressant
Anxiety
Autophagy
BDNF
calorie restriction
Calories
Cognitive ability
Cytokines
Diet
Dietary restrictions
Disease
Energy
Fasting
Food
Gene expression
Kinases
Ligands
Malnutrition
Mental depression
Mental disorders
Neurogenesis
Neurological disorders
Phosphorylation
Proteins
Psychiatry
Quality of life
Review
Reviews
Weight control
fasting
calorie restriction
BDNF
antidepressant
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Summary:Recently, most of evidence shows that caloric restriction could induce antidepressant‐like effects in animal model of depression. Based on studies of the brain–gut axis, some signal pathways were common between the control of caloric restriction and depression. However, the specific mechanism of the antidepressant‐like effects induced by caloric restriction remains unclear. Therefore, in this article, we summarized clinical and experimental studies of caloric restriction on depression. This review may provide a new therapeutic strategy for depression.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:1582-1838
1582-4934
DOI:10.1111/jcmm.13418