Cholinesterase activity in pig airways and epithelial cells

• Published in: Fundamental & clinical pharmacology Vol. 11; no. 3; pp. 201 - 205
• Main Authors: Taisne, C., Norel, X., Walch, L., Labat, C., Verriest, C., Mazmanian, GM, Brink, C.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.01.1997; Blackwell
• Subjects: acetylcholinesterase; Acetylcholinesterase - metabolism; airways; Analytical, structural and metabolic biochemistry; Animals; Biological and medical sciences; Bronchi - cytology; Bronchi - drug effects; Bronchi - enzymology; butyrylcholinesterase; Butyrylcholinesterase - metabolism; Cells, Cultured; Cyclooxygenase Inhibitors - pharmacology; Enzymes and enzyme inhibitors; Epithelial Cells; epithelium; Epithelium - drug effects; Epithelium - enzymology; Fundamental and applied biological sciences. Psychology; Hydrolases; indomethacin; Indomethacin - pharmacology; Kinetics; Muscle, Smooth - cytology; Muscle, Smooth - drug effects; Muscle, Smooth - enzymology; Swine; Enzyme; Indometacin; Bronchus; Esterases; In vitro; Cholinesterase; Carboxylic ester hydrolases; Pig; Respiratory tract; Vertebrata; Mammalia; Enzymatic activity; Animal; Indoleacetic acid derivatives; Hydrolases; Epithelial cell; Artiodactyla; Ungulata; Biological constant

Summary— Acetylcholinesterase (AChE, EC 3.1.1.7) and butyrylcholinesterase (BChE, EC 3.1.1.8) activities were detected in bronchial and bronchial epithelial cell homogenates of the pig. In the bronchial homogenates, the maximal upstroke velocity (Vmax) of AChE and the maximal velocity after second s...