Impact of area strain by 3D speckle tracking on clinical outcome in patients after acute myocardial infarction
Background Three‐dimensional (3D) speckle tracking echocardiography (STE) has been developed to overcome the limitations of two‐dimensional (2D) STE and has been applied in the several clinical settings. However, no data exist about the prognostic value of 3DSTE‐based strain on clinical outcome afte...
Saved in:
Published in | Echocardiography (Mount Kisco, N.Y.) Vol. 33; no. 12; pp. 1854 - 1859 |
---|---|
Main Authors | , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
United States
Blackwell Publishing Ltd
01.12.2016
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | Background
Three‐dimensional (3D) speckle tracking echocardiography (STE) has been developed to overcome the limitations of two‐dimensional (2D) STE and has been applied in the several clinical settings. However, no data exist about the prognostic value of 3DSTE‐based strain on clinical outcome after myocardial infarction (MI). This study was designed to investigate the prognostic value of area strain (AS) by 3D speckle tracking in predicting clinical outcome after acute MI.
Methods
We assessed 96 patients (62±14 years, 72% male) with acute MI and who had undergone a coronary angiography. Clinical parameters and conventional echocardiographic measurements including the left atrial (LA) size and tissue Doppler measurements were evaluated. The global left ventricular (LV) AS was measured using 3D speckle tracking software. The relationship between the AS and clinical outcome of death or hospitalization for heart failure (HF) was assessed.
Results
During a median follow‐up of 33±10 months, primary endpoint of death or HF occurred in 12 patients (12.5%). AS was predictive of death or HF after adjustment for age, gender, peak CK‐MB, LA volume, LV end‐systolic volume, LV mass, the ratio of early mitral inflow velocity to early mitral annular velocity, and LV ejection fraction in a multivariate Cox model (HR 1.23, 95% CI 1.02–1.47, P=.03). In addition, AS added incremental value in predicting death or heart failure on a model based on clinical and standard echocardiographic measures (P=.008).
Conclusion
AS is independently associated with increased risk of death or HF after acute MI, suggesting that it can be a useful prognostic parameter in the patients following MI. |
---|---|
Bibliography: | ark:/67375/WNG-4F6N0645-Q Inha University Research Grant - No. INHA 42821-01 ArticleID:ECHO13354 istex:33AABBD2777188B864A0DAB689E6D268E77738B1 ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0742-2822 1540-8175 |
DOI: | 10.1111/echo.13354 |