A combined occurrence of neuroendocrine carcinoma of the skin and a benign appendageal neoplasm

A 76-year-old Japanese male presented with a subcutaneous nodule in the dorsal cubital region of the right arm. The center of the nodule showed typical features of neuroendocrine carcinoma of the skin. The peripheral portion showed epithelial islands of squamoid cells with horn cysts suggestive of b...

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Bibliographic Details
Published inJournal of cutaneous pathology Vol. 20; no. 2; p. 173
Main Authors Yamamoto, O, Tanimoto, A, Yasuda, H, Suenaga, Y, Asahi, M
Format Journal Article
LanguageEnglish
Published United States 01.04.1993
Subjects
Aged
Carcinoma, Merkel Cell - pathology
Hamartoma - pathology
Humans
Male
Microscopy, Electron
Neoplasms, Multiple Primary - pathology
Skin Neoplasms - pathology
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Summary:A 76-year-old Japanese male presented with a subcutaneous nodule in the dorsal cubital region of the right arm. The center of the nodule showed typical features of neuroendocrine carcinoma of the skin. The peripheral portion showed epithelial islands of squamoid cells with horn cysts suggestive of benign appendageal tumor with pilar differentiation. The coexistence of two skin neoplasms in the same lesion would suggest that both tumors developed from common pluripotential stem cell.
ISSN:0303-6987
DOI:10.1111/j.1600-0560.1993.tb00237.x