Effect of Coenzyme Q10 on Proteomic Profile of Rat Plasma under Conditions of Metabolic Stress

Proteomic profile of rat plasma was evaluated under conditions of metabolic stress (5-day starvation) and administration of coenzyme Q10 in doses of 10 and 100 mg/kg. This antioxidant and geroprotector plays a key role in cell metabolism. The expression of some low-molecularweight proteins in respon...

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Published inBulletin of experimental biology and medicine Vol. 151; no. 6; pp. 680 - 682
Main Authors Sharanova, N. E., Baturina, V. A., Vasil’ev, A. V., Gapparov, M. M. G.
Format Journal Article
LanguageEnglish
Published Boston Springer US 01.10.2011
Springer
Springer Nature B.V
Subjects
Animals
Antioxidants
Antioxidants - pharmacology
Biomedical and Life Sciences
Biomedicine
Biophysics and Biochemistry
Cell Biology
Electron transport
Electrophoresis, Gel, Two-Dimensional
Enzymes
Internal Medicine
Laboratory Medicine
Oxidative Stress - drug effects
Pathology
Physiological aspects
Proteome - drug effects
Proteomics
Rats
Starvation
Ubiquinone - analogs & derivatives
Ubiquinone - pharmacology
proteomic profile
stress
coenzyme Q10
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Summary:Proteomic profile of rat plasma was evaluated under conditions of metabolic stress (5-day starvation) and administration of coenzyme Q10 in doses of 10 and 100 mg/kg. This antioxidant and geroprotector plays a key role in cell metabolism. The expression of some low-molecularweight proteins in response to treatment with coenzyme Q10 was observed.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0007-4888
1573-8221
DOI:10.1007/s10517-011-1414-9