Leukoerythroblastosis as an Unusual Presentation of Parvovirus B19 Infection in a Sickle Cell Patient

Parvovirus B19 infection in pediatrics most commonly causes fifth disease, a mild viral illness. Hematologic manifestations include severe anemia, especially in patients with chronic hemolytic anemias or who are immunocompromised. Because of the shortened life span of erythrocytes in patients with s...

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Bibliographic Details
Published inCase reports in pediatrics Vol. 2020; no. 2020; pp. 1 - 3
Main Authors Patel, Pratik A., Wechsler, Daniel S., Weinzierl, Elizabeth P.
Format Journal Article
LanguageEnglish
Published Cairo, Egypt Hindawi Publishing Corporation 22.09.2020
Hindawi
John Wiley & Sons, Inc
Hindawi Limited
Subjects
Anemia
Blood
Case Report
Case reports
Deoxyribonucleic acid
DNA
Hematology
Hemoglobin
Hyperactivity
Infection
Infections
Infectious diseases
Leukemia
Patients
Pediatrics
Premature labor
Sickle cell anemia
Sickle cell disease
Tumors
Viral infections
Atlanta Georgia
United States > US
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Summary:Parvovirus B19 infection in pediatrics most commonly causes fifth disease, a mild viral illness. Hematologic manifestations include severe anemia, especially in patients with chronic hemolytic anemias or who are immunocompromised. Because of the shortened life span of erythrocytes in patients with sickle cell disease, parvovirus infection can cause transient aplastic crisis which can be life-threatening. However, leukocytosis and thrombocytosis are rarely seen. We report leukoerythroblastosis as an unusual presentation of acute parvovirus B19 infection in a previously splenectomized 12-year-old boy with sickle cell disease.
Bibliography:Academic Editor: Marie Louise von Linstow
ISSN:2090-6803
2090-6811
DOI:10.1155/2020/8841607