Recurrence of Primary Vascular Leiomyosarcoma Five Years after Initial Diagnosis in the Lower Extremity

Primary leiomyosarcomas of vascular origin are rare tumors. They frequently arise within the inferior vena cava; however, the peripheral vein was also affected. To date, only a few hundred cases have been reported in the world literature. Although it is an extremely aggressive tumor, the symptoms ma...

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Published inCase reports in oncological medicine Vol. 2018; no. 2018; pp. 1 - 3
Main Authors Erinanç, Hilal, Terzi, Aysen, Özülkü, Mehmet
Format Journal Article
LanguageEnglish
Published Cairo, Egypt Hindawi Publishing Corporation 01.01.2018
Hindawi
Hindawi Limited
Wiley
Subjects
Case Report
Case reports
Chemotherapy
Diagnosis
Immunohistochemistry
Leiomyosarcoma
Medical prognosis
Metastasis
NMR
Nuclear magnetic resonance
Oncology
Patients
Radiation therapy
Recurrence (Disease)
Smooth muscle
Surgery
Thrombosis
Tumors
Varicose veins
Vascular surgery
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Summary:Primary leiomyosarcomas of vascular origin are rare tumors. They frequently arise within the inferior vena cava; however, the peripheral vein was also affected. To date, only a few hundred cases have been reported in the world literature. Although it is an extremely aggressive tumor, the symptoms may be unspecific, especially in the lower extremities. In this report, we present a case of primary vascular leiomyosarcoma, arising from the short saphenous vein, with symptoms mimicking thrombus in the initial diagnosis. The diagnosis of leiomyosarcomas was confirmed by standard H&E staining and immunohistochemical staining. Recurrence of the tumor has been observed five years after surgical treatment. Due to its rarity, experience in the management of this type of tumor is limited. The mainstay of treatment for these tumors is complete surgical resection. The purpose of the presented case is to discuss the clinicopathological features and management options of this tumor, under the light of the most recent literatures.
Bibliography:Academic Editor: Raffaele Palmirotta
ISSN:2090-6706
2090-6714
DOI:10.1155/2018/3094616