Biocompatible nanomaterials based on dendrimers, hydrogels and hydrogel nanocomposites for use in biomedicine

• Published in: Advances in natural sciences. Nanoscience and nanotechnology Vol. 8; no. 1; p. 015001
• Main Authors: Nguyen, Cuu Khoa, Tran, Ngoc Quyen, Nguyen, Thi Phuong, Nguyen, Dai Hai
• Format: Journal Article
• Language: English
• Published: Hanoi IOP Publishing 01.03.2017
• Subjects: Biocompatibility; Biodegradability; Biodegradation; Biomedical engineering; Biomedical materials; biomedicine; biopolymer-based nanomaterials; Biopolymers; Biotechnology; Dendrimers; Drug delivery; Drug delivery systems; hydrogel nanocomposites; Hydrogels; In vivo methods and tests; Nanocomposites; Nanomaterials; Nanotechnology; Surgical implants; Tissue engineering; Toxicity
• ISSN: 2043-6262; 2043-6254; 2043-6254; 2043-6262
• DOI: 10.1088/2043-6254/8/1/015001

Over the past decades, biopolymer-based nanomaterials have been developed to overcome the limitations of other macro- and micro- synthetic materials as well as the ever increasing demand for the new materials in nanotechnology, biotechnology, biomedicine and others. Owning to their high stability, biodegradability, low toxicity, and biocompatibility, biopolymer-based nanomaterials hold great promise for various biomedical applications. The pursuit of this review is to briefly describe our recent studies regarding biocompatible biopolymer-based nanomaterials, particularly in the form of dendrimers, hydrogels, and hydrogel composites along with the synthetic and modification approaches for the utilization in drug delivery, tissue engineering, and biomedical implants. Moreover, in vitro and in vivo studies for the toxicity evaluation are also discussed.