4-Methylbenzylidene camphor microspheres: reconstituted epidermis (Skinethic®) permeation and distribution

• Published in: International journal of cosmetic science Vol. 37; no. 3; pp. 298 - 305
• Main Authors: Monti, D., Chetoni, P., Burgalassi, S., Tampucci, S., Centini, M., Anselmi, C.
• Format: Journal Article
• Language: English
• Published: England Blackwell Publishing Ltd 01.06.2015
• Subjects: 4-methylbenzylidene camphor; Camphor - analogs & derivatives; Camphor - pharmacokinetics; Epidermis - metabolism; Humans; Microspheres; Models, Biological; permeation; reconstituted epidermis; Skin Absorption; skin distribution; Sunscreening Agents - pharmacokinetics; Tissue Distribution; reconstituted epidermis; microspheres; permeation; 4-methylbenzylidene camphor; skin distribution

Synopsis Objective The UV filter 3(4‐methylbenzylidene) camphor (4‐MBC) is a common ingredient in sunscreen cosmetic products. However, different ‘in vitro’ and ‘in vivo’ studies suggest that 4‐MBC can cause endocrine disrupting effects. Therefore, there is a need for new systems able to minimize th...