Synthesis and biological evaluation of novel N-pyridylpyrazole derivatives containing 1,2,3-triazole moieties

Based on the commercial insecticide chlorantraniliprole, a series of novel N-pyridylpyrazole derivatives containing 1,2,3-triazole moieties were designed and synthesized via Huisgen cycloaddition reaction. The insecticidal activities of the new compounds against the oriental armyworm (Mythimna separ...

Full description

Saved in:
Bibliographic Details
Published inJournal of Pesticide Science Vol. 40; no. 3; pp. 138 - 142
Main Authors Mao, Mingzhen, Li, Yuxin, Liu, Qiaoxia, Xiong, Lixia, Zhang, Xiao, Li, Zhengming
Format Journal Article
LanguageEnglish
Published Tokyo Pesticide Science Society of Japan 01.01.2015
Japan Science and Technology Agency
Subjects
1,2,3-triazole
biological activity
Insecticides
isosterism
Mythimna separata
N-pyridylpyrazole derivatives
Online AccessGet full text

Cover

More Information
Summary:Based on the commercial insecticide chlorantraniliprole, a series of novel N-pyridylpyrazole derivatives containing 1,2,3-triazole moieties were designed and synthesized via Huisgen cycloaddition reaction. The insecticidal activities of the new compounds against the oriental armyworm (Mythimna separata) were evaluated, of which compound Ib with an N-isopropyl anthranilic amide moiety displayed 100% larvicidal activities against Mythimna separata at a concentration of 10 mg/L. Moreover, the fungicidal activities of some target compounds in vitro against five fungi at 50 µg⁄mL indicated that some compounds exhibited moderate fungicidal activities.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
content type line 23
ISSN:1348-589X
1349-0923
DOI:10.1584/jpestics.D15-020