Rap1a Is a Key Regulator of Fibroblast Growth Factor 2-Induced Angiogenesis and Together with Rap1b Controls Human Endothelial Cell Functions

• Published in: Molecular and Cellular Biology Vol. 28; no. 18; pp. 5803 - 5810
• Main Authors: Yan, Jingliang, Li, Fang, Ingram, David A., Quilliam, Lawrence A.
• Format: Journal Article
• Language: English
• Published: United States American Society for Microbiology 01.09.2008; Taylor & Francis; American Society for Microbiology (ASM)
• Subjects: Animals; Aorta - anatomy & histology; Aorta - metabolism; Cell Adhesion - physiology; Cell Movement - physiology; Cells, Cultured; Endothelial Cells - cytology; Endothelial Cells - physiology; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases - genetics; Extracellular Signal-Regulated MAP Kinases - metabolism; Fibroblast Growth Factor 2 - genetics; Fibroblast Growth Factor 2 - metabolism; Humans; Mice; Mice, Inbred C57BL; Mice, Knockout; Neovascularization, Physiologic - physiology; p38 Mitogen-Activated Protein Kinases - genetics; p38 Mitogen-Activated Protein Kinases - metabolism; rac GTP-Binding Proteins - genetics; rac GTP-Binding Proteins - metabolism; rap GTP-Binding Proteins - genetics; rap GTP-Binding Proteins - metabolism; rap1 GTP-Binding Proteins - genetics; rap1 GTP-Binding Proteins - metabolism; RNA, Small Interfering - genetics; RNA, Small Interfering - metabolism; Signal Transduction - physiology
• ISSN: 0270-7306; 1098-5549; 1098-5549
• DOI: 10.1128/MCB.00393-08

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