Bilateral benign non functional struma ovarii with Pseudo-Meigs' syndrome

• Published in: Indian journal of pathology & microbiology Vol. 52; no. 1; pp. 94 - 96
• Main Authors: Rana, Vandana, Srinivas, V, Bandyopadhyay, S, Ghosh, S K, Singh, Yashpal
• Format: Journal Article
• Language: English
• Published: India Medknow Publications and Media Pvt. Ltd 01.01.2009; Wolters Kluwer Medknow Publications
• Subjects: Aged; Bilateral struma ovarii; CA 125; CA-125 Antigen - blood; Care and treatment; Case studies; CT imaging; Diagnosis; Excision (Surgery); Female; Health aspects; Humans; Meigs Syndrome - pathology; Ovarian Neoplasms - diagnosis; Ovarian Neoplasms - pathology; Ovarian Neoplasms - surgery; Ovarian tumors; Pelvis - diagnostic imaging; Pseudo-Meigs′ syndrome; Radiography, Abdominal; Risk factors; Struma Ovarii - complications; Struma Ovarii - diagnosis; Struma Ovarii - pathology; Struma Ovarii - surgery; Tomography, X-Ray Computed; India
• ISSN: 0377-4929; 0974-5130
• DOI: 10.4103/0377-4929.44978

Bilateral presentation of benign Struma ovarii is rare and has not been reported frequently in published literature. A 70-year-old postmenopausal female presented with progressive ascites, bilateral pleural effusion and elevated CA-125 levels. The contrast-enhanced computed tomography (CECT) of the abdomen and pelvis revealed a heterogenous mass in the left adnexa. These findings were suspicious for an ovarian malignancy. After surgery the diagnosis of non functional, bilateral benign Struma ovarii was made. Struma ovarii is a specialized ovarian teratoma composed predominantly of mature thyroid tissue. It is associated with pleural effusion and ascites (Pseudo-Meigs' syndrome) in 5% of cases. The combination of struma ovarii and elevated CA-125 levels has been reported infrequently. This is a rare case of bilateral benign struma ovarii associated with Pseudo-Meigs' syndrome and elevated CA-125 levels. Surgical excision of the ovarian masses induced immediate resolution of the ascites and pleural effusion and a reduction of the serum CA-125 level.