Clinical Impact of Staphylococcus aureus Skin and Soft Tissue Infections

• Published in: Antibiotics (Basel) Vol. 12; no. 3; p. 557
• Main Authors: Linz, Matthew S, Mattappallil, Arun, Finkel, Diana, Parker, Dane
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 11.03.2023; MDPI
• Subjects: Abscesses; Antibiotic resistance; Antibiotics; Antimicrobial agents; antimicrobial resistance; bacterial pathogenesis; Cell walls; Cellulitis; Cephalosporins; clinical presentation; Complications; Cost estimates; Dendritic cells; Diabetes; Drug resistance; E coli; Epidemics; Fasciitis; Fatalities; Health risks; Hospital costs; Hospitalization; Immune response; Immune system; Infections; Keratinocytes; Kidney diseases; Leukocytes (neutrophilic); Lymphocytes; Lymphocytes T; Methicillin; Mortality; Necrotizing fasciitis; Oxacillin; Pathogens; Penicillin; Pneumonia; Proteins; Public health; Review; Risk factors; Skin; skin-and-soft-tissue infections; Soft tissues; Staphylococcus aureus; Staphylococcus infections; Staphylococcus aureus; Streptococcus infections; Systematic review; treatment; Vancomycin; Virulence factors; Australia; United States > US; Staphylococcus aureus; epidemiology; treatment; clinical presentation; antimicrobial resistance; bacterial pathogenesis; antibiotics; skin-and-soft-tissue infections

The pathogenic bacterium is the most common pathogen isolated in skin-and-soft-tissue infections (SSTIs) in the United States. Most SSTIs are caused by the epidemic clone USA300 in the USA. These infections can be serious; in 2019, SSTIs with were associated with an all-cause, age-standardized morta...