Single or Double Arteries in the Remnant Kidney After Donation: Influence on the Long-Term Outcome of the Donor

• Published in: Transplantation proceedings Vol. 41; no. 2; pp. 764 - 765
• Main Authors: Fehrman-Ekholm, I, Möller, S, Steinwall, J, Nordén, G, Lennerling, A, Holmdahl, J, Kvarnström, N, Olausson, M
• Format: Journal Article Conference Proceeding
• Language: English
• Published: Amsterdam Elsevier Inc 01.03.2009; Elsevier
• Subjects: abnormalities; Adult; Age Factors; Biological and medical sciences; blood; Blood Pressure; Creatinine; Creatinine - blood; Dermatologi och venereologi; Dermatology and Venereal Diseases; epidemiology; Follow-Up Studies; Fundamental and applied biological sciences. Psychology; Fundamental immunology; Glomerular Filtration Rate; Humans; Hypertension; Hypertension - epidemiology; Kidney; Kidney - physiology; Kidney Function Tests; Kidneys; Living Donors; Malformations of the urinary system; MEDICAL AND HEALTH SCIENCES; Medical sciences; MEDICIN OCH HÄLSOVETENSKAP; Middle Aged; Nephrectomy; Nephrology. Urinary tract diseases; physiology; Postoperative Complications; Postoperative Complications - epidemiology; Renal Artery; Renal Artery - abnormalities; Renal Artery - physiology; Renal Circulation; Renal Circulation - physiology; Surgery; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Tissue and Organ Harvesting; Tissue, organ and graft immunology; Kidney disease; Suboptimal donor; Human; Urinary system disease; Prognosis; Double kidney; Transplantation; Congenital disease; Long term; Artery; Medicine; Persistence; Treatment; Malformation; Surgery; Blood vessel; Evolution; Graft; Circulatory system
• ISSN: 0041-1345; 1873-2623
• DOI: 10.1016/j.transproceed.2009.01.033

Abstract Background A kidney with a single artery is preferred for donation. We wondered how often the donor is left with double or triple arteries, and whether this has any implications for long-term kidney function. Methods The consecutive living donors from 1984 to 1988 were reevaluated for kidney function and outcome. Results In total, 154 donor nephrectomies were performed with an open anterior technique. Ninety-eight patients were left with a single artery to the remnant kidney and 56 (36%) with more than one. Six individuals were left with 3 arteries. The mean age at donation was 48 ± 12 years and mean age at reevaluation was 68 ± SD 12 years. In the group with a remnant single artery, the mean preoperative serum creatinine level was 87 ± 11 μmol/L, at 6 months it was 127 ± 20 μmol/L, and in 2007 it was 90 ± SD 23 μmol/L. The estimated glomerular filtration rate (GFR) was 67 ± 18 mL/min. Thirty-three percent of donors (19/58) had developed hypertension. Among the group with multiple remnant arteries, the mean preoperative serum creatinine level was 87 ± SD 11 μmol/L, at 6 months it was 131 ± 21 μmol/L, and in 2007 it was 100 ± 45 μmol/L. Estimated GFR was 64 ± 16) mL/min. Twenty-eight percent of the donors (10/36) had developed hypertension. Conclusions One third of kidney donors were left with double or triple arteries to the remnant kidney. The 20-year follow-up showed no significant difference in the renal function between the 2 groups.