Latent Blue and Red Fluorophores Based on the Trimethyl Lock

Unlocking fluorescence. The “trimethyl lock” is an effective way to mask structurally diverse fluorescent molecules for the preparation of fluorogenic enzyme substrates. These novel probes exhibit remarkable stability in water, and this makes them useful for a variety of biochemical and biological a...

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Bibliographic Details
Published inChembiochem : a European journal of chemical biology Vol. 7; no. 8; pp. 1151 - 1154
Main Authors Lavis, Luke D, Chao, Tzu-Yuan, Raines, Ronald T
Format Journal Article
LanguageEnglish
Published Weinheim Wiley-VCH Verlag 01.08.2006
WILEY-VCH Verlag
WILEY‐VCH Verlag
Subjects
Animals
Cell Line, Tumor
Color
enzyme catalysis
Fluorescence
Fluorescent Dyes - chemical synthesis
Fluorescent Dyes - chemistry
fluorescent probes
fluorogenic substrates
Humans
imaging
Kinetics
Methylation
Molecular Structure
trimethyl lock
Umbelliferones - chemistry
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Summary:Unlocking fluorescence. The “trimethyl lock” is an effective way to mask structurally diverse fluorescent molecules for the preparation of fluorogenic enzyme substrates. These novel probes exhibit remarkable stability in water, and this makes them useful for a variety of biochemical and biological applications.
Bibliography:http://dx.doi.org/10.1002/cbic.200500559
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ArticleID:CBIC200500559
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SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1439-4227
1439-7633
DOI:10.1002/cbic.200500559